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Thymalin

Thymalin

Basic Info. Thymulin (also known as thymic factor or its old name facteur thymique serique) is a nonapeptide produced by two distinct epithelial populations in the thymus first described by Bach in 1977. The hormone is believed to be involved in T-cell differentiation and enhancement of T and NK cell actions. Besides this rather paracrine or auto-organic effects on the thymus dependent immune system, thymulin seems to have neuroendocrine effects as well.   There exist bidirectional interactions between thymic epithelium and the hypothalamus-pituitary axis. ...

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Thymosin Alpha-1

Thymosin Alpha-1

Basic Info. Thymosin alpha 1 (T¦Á1) is a naturally occurring peptide produced in the thymus gland and is known for its immunomodulatory properties.   It's a small protein of 28 amino acids that helps enhance the immune response by stimulating T cells, which are crucial for adaptive immunity.  T¦Á1 has been used in various clinical applications, including treating immunocompromised states, infections, and cancers.   ...

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MOTS-c

MOTS-c

Basic Info. MOTS-c is a 16 amino acid peptide that is coded by the mitochondrial genome. The mitochondria are the ¡°power generators¡± in cells that convert chemical energy from food into a form that cells can use.  Two other mitochondrial-derived peptides (MDPs) have also been discovered so far, humanin and SHLP1-6, but their possible involvement in human performance enhancement is unknown. According to new research, mitochondrial-derived peptides such as MOTS-c have a role in maintaining mitochondrial function and protecting cells under different stresses 1 .   It has been shown that exercise causes MOTS-c levels to go up in humans. Furthermore, it has been shown in mice that MOTS-c treatment improves physical performance in mice of all ages and seems to regulate skeletal muscle metabolism and gene expression. ...

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Retatrutide

Retatrutide

Basic Info. Retatrutide is an experimental drug developed by Eli Lilly and Company in the United States for the treatment of obesity. It is a triple glucagon hormone receptor agonist. In a phase II clinical trial, the drug has been proved to reduce the average weight of non diabetes but obese or pre obese (overweight) adults by more than 17.5% ...

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melatonin

melatonin

Basic Info. Melatonin: Understand the Sleep Hormone and Its Benefits Melatonin is a hormone naturally produced in the body, primarily by the pineal gland, that plays a crucial role in regulating the sleep-wake cycle, also known as the circadian rhythm. It helps the body know when to sleep and when to wake up. Melatonin is also available as a supplement, and it is often taken to help with sleep problems, jet lag, and shift work-related sleep disturbances.  ...

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Glutathione

Glutathione

Basic Info. Glutathione is a substance made from the amino acids glycine, cysteine, and glutamic acid. It is produced by the liver and involved in many body processes. Glutathione is involved in tissue building and repair, making chemicals and proteins needed in the body, and in immune system function. ...

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ÎÞ¾úË®

ÎÞ¾úË®

Basic Info. Sterile water usually refers to water without bacteria obtained by treating water containing bacteria by physical methods, such as steam method, UHT heat method, ultraviolet sterilization, ozone method and physical filtration method, which kills microorganisms in water and filters it, and the inorganic salts in the water generally do not decrease. ...

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5-amino-1MQ

5-amino-1MQ

Basic Info. 5-amino-1MQ is a small molecule drug that functions to block the activity of an enzyme called nicotinamide N-methyltransferase (NNMT). NNMT plays a significant role in metabolism and energy and is predominantly active in fat tissue.  By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as ¡®the longevity gene¡¯ because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease,  neurodegeneration, and cancer. ...

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Cerebrolysin

Cerebrolysin

Basic Info. Cerebrolysin, a neuropeptide preparation, has been extensively studied in rat models to evaluate its potential in treating neurological impairments. Research indicates that Cerebrolysin can significantly enhance cognitive functions and promote neuroprotection following brain injuries. It is rats subjected to mild traumatic brain injury (mTBI) were treated with Cerebrolysin. The results demonstrated notable improvements in long-term spatial learning and memory, as assessed by the Morris water maze test.  Additionally, treated rats exhibited reduced accumulation of amyloid precursor protein and decreased astrogliosis, suggesting neuroprotective effects. ...

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Ara-290

Ara-290

Basic Info. ARA 290, a Nonerythropoietic Peptide Engineered from Erythropoietin, Improves Metabolic Control and Neuropathic Symptoms in Patients with Type 2 Diabetes. ARA 290  has been shown to be effective in the reduction of inflammation and activation of the healing process in a wide variety of preclinical models as well as in patients.  With respect to diabetes, substantial recent work has shown that rhEPO can improve the diabetic state in animal models . However, in addition to interacting with the innate repair receptor in a paracrine/autocrine manner, EPO also functions as a circulating hormone via its interaction with the EPO receptor homodimer that mediates hematopoiesis. ...

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Cagrilintide

Cagrilintide

Basic Info. Cagrilintide, a long-acting analogue of the hormone amylin, presents a promising new approach to tackling obesity.  Unlike many weight-loss drugs that only target one mechanism, cagrilintide works on multiple fronts. It suppresses appetite by promoting feelings of fullness (satiety) and slows down gastric emptying, making people feel full for longer periods of time.  Early trials of cagrilintide have shown that it leads to significant weight loss compared to placebo and even other peptides like liraglutide, which is currently used for obesity treatment. In one study, participants taking cagrilintide lost up to 10.8% of their body weight over 26 weeks, outperforming those on liraglutide. Sustained weight loss like this can help break the cycle of yo-yo dieting. ...

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NAD

NAD

Basic Info. NAD, the full name of nicotinamide adenine dinucleotide, is an important coenzyme that participates in a variety of metabolic processes in cells, such as energy production, DNA repair, and cell signaling. NAD usually exists in two forms, NAD+ and NADH, which play an important role in electron transfer in cells. NAD is an important coenzyme that participates in a variety of metabolic processes in cells and is essential for health. By supplementing NAD+ or NMN, the level of NAD+ in the body can be increased, thereby improving health and delaying aging. ...

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